23/9/2025
Xmin
A doctor performs a lung ultrasound with echOpen
POCUS

Understanding the BLUE Protocol in intensive care

Clinical ultrasound plays a crucial role in the case of a patient presenting with a respiratory condition, a common and potentially serious picture that can be caused by a variety of respiratory and cardiovascular pathologies. Using ultrasound, resuscitation physicians can quickly and efficiently assess the lungs, heart and other thoracic structures to identify the underlying cause of symptoms. 

Lung ultrasound, for example, can detect abnormalities such as pneumothorax, pleural effusions and pneumonia, while echocardiography can reveal cardiac dysfunctions such as heart failure or valvulopathy. This non-invasive technique enables rapid and accurate management, reducing diagnostic delays and improving the chances of effective treatment and patient recovery.

Le protocole BLUE, décrit pour la première fois par Daniel Lichtenstein en 2008, est rapidement devenu une référence mondiale en échographie pulmonaire d’urgence. Sa simplicité et sa standardisation en font un outil adapté aussi bien aux réanimateurs expérimentés qu’aux médecins en formation.

In this article, we'll explore the BLUE ultrasound protocol, a valuable tool for intensive care physicians. We'll look at its definition, its decision tree, and its link with PLAPS. We'll also look at the value of the BLUE protocol in the ICU, the different profiles of the protocol, and examples of BLUE examinations.

What is the BLUE protocol in ultrasound?

BLUE (Bedside Lung Ultrasound in Emergency) is a lung ultrasound protocol used in emergency situations. It enables rapid and effective diagnosis of common lung pathologies. The BLUE protocol is based on the analysis of six thoracic points (three bilateral zones) to detect abnormalities such as pneumothorax, pleural effusions, alveolar syndromes (e.g. pneumonia) and interstitial syndromes (e.g. pulmonary edema).

Le protocole BLUE repose sur un principe simple : « un point, une réponse ». L’analyse systématique des six zones thoraciques permet de réduire l’incertitude diagnostique dans plus de 90 % des cas de dyspnée aiguë.

Echopneumology is an ultrasound specialty that focuses on lung imaging. The BLUE protocol is a key tool in this specialty, enabling rapid and accurate diagnosis in emergency situations. It is particularly useful for resuscitators, emergency physicians and pulmonologists (who often use an adapted variant of the protocol), who often have to make rapid decisions based on limited information.

The decision tree

The BLUE protocol is based on a decision tree that guides the physician through a series of questions and observations. Here are the key steps in the decision tree:

Please note that the BLUE protocol has not been designed to provide a 100% reliable diagnosis of dyspnea. It has been simplified and simplified with the aim of achieving 90.5% reliability.

Concrètement, l’arbre décisionnel permet en quelques minutes de distinguer les causes respiratoires (pneumonie, pneumothorax, œdème pulmonaire) des causes cardiaques (insuffisance ventriculaire gauche) ou mixtes. Cela évite des examens longs et invasifs, et oriente directement le patient vers la bonne stratégie thérapeutique.

Link with PLAPS Point

The PLAPS point (Postero-Lateral Alveolar and/or Pleural Syndrome) is a specific point used in the BLUE protocol to detect alveolar and pleural abnormalities. It is located on the postero-lateral chest wall and is used to detect pathologies such as pneumonia and pleural effusions. The PLAPS point is a key element in the BLUE protocol decision tree, providing crucial information for diagnosis.

Benefits of the BLUE Protocol in Emergency Ultrasound

The BLUE protocol is particularly useful in intensive care and emergency medicine for several reasons:

- Speed: It enables rapid diagnosis, which is essential in emergency situations.

- Accuracy: It provides precise information on lung pathologies, enabling you to make informed decisions.

- Non-invasive: Ultrasound is a non-invasive technique, making it safe and comfortable for patients.

Le protocole BLUE est aussi particulièrement utile dans les environnements à ressources limitées (soins préhospitaliers, médecine humanitaire, zones rurales). Il ne nécessite qu’un échographe portable et une formation adaptée, ce qui en fait une méthode accessible et reproductible partout dans le monde.

The different BLUE Protocol profiles

The BLUE protocol can be used to diagnose several pulmonary pathology profiles. Here are the main profiles:

- Profile A: Characterized by a normal pleural line and A artifacts. This profile is often associated with pneumothorax.

- B profile: Characterized by B lines, which are vertical artifacts. This profile is often associated with pulmonary edema.

- Profile C: Characterized by alveolar consolidations. This profile is often associated with pneumonia.

- A/B profile: Characterized by a combination of A and B lines. This profile is often associated with heart failure.

- PLAPS profile: Characterized by alveolar and pleural abnormalities. This profile is often associated with pneumonia or pleural effusion.

En pratique clinique, ces profils ne sont pas toujours exclusifs. Il est fréquent d’observer des combinaisons de signes, notamment dans les cas complexes de détresse respiratoire aiguë. La répétition de l’examen au cours de l’évolution clinique permet de suivre l’efficacité du traitement et d’adapter la prise en charge.

Conclusion

The BLUE protocol is an interesting tool for intensive care physicians, emergency physicians and pulmonologists. It enables rapid and accurate diagnosis, using a decision tree based on the analysis of six specific points on the chest wall. The PLAPS point is a key element in this decision tree, providing crucial information for diagnosis. By understanding the different profiles of the BLUE protocol and using concrete examples, healthcare professionals can improve their practice and offer better quality care to their patients.

Avec la démocratisation des échographes ultraportables, comme la sonde echOpen O1, le protocole BLUE devient encore plus facile à intégrer en pratique quotidienne. Léger, accessible et connecté, un échographe portable permet de réaliser l’examen immédiatement au lit du patient, renforçant ainsi la place de l’échographie pulmonaire dans la réanimation moderne.